Antiretroviral drug-drug interactions in an era of polypharmacy

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Polypharmacy in Bipolar Disorder - a Focus on Drug - Drug Interactions

Background: Drug-drug interactions (DDI) are actually quite commonplace and are responsible for considerable patient morbidity and mortality. The two major varieties of DDI are pharmacodynamic and pharmacokinetic interactions (cytochrome P450 system). Conditions such as bipolar disorder (with many psychiatric and somatic comorbidities) are complex symptom clusters and bipolar patients may need ...

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Drug-drug interactions and adverse drug reactions in polypharmacy among older adults: an integrative review 1

OBJECTIVE to identify and summarize studies examining both drug-drug interactions (DDI) and adverse drug reactions (ADR) in older adults polymedicated. METHODS an integrative review of studies published from January 2008 to December 2013, according to inclusion and exclusion criteria, in MEDLINE and EMBASE electronic databases were performed. RESULTS forty-seven full-text studies including ...

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ژورنال

عنوان ژورنال: Germs

سال: 2019

ISSN: 2248-2997

DOI: 10.18683/germs.2019.1166